General Information

  • ID:  hor001089
  • Uniprot ID:  NA
  • Protein name:  FMRFamide-related peptide
  • Gene name:  NA
  • Organism:  Locusta migratoria
  • Family:  FMRFamide related peptide family
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  NA
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  ADVGHVFLRF
  • Length:  10
  • Propeptide:  NA
  • Signal peptide:  NA
  • Modification:  T10 Phenylalanine amide
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  Have an inhibitory effect, decreasing the amplitude of neurally evoked spermathecal contractions.
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor001089_AF2.pdbhor001089_ESM.pdb

Physical Information

Mass: 132106 Formula: C55H81N15O13
Absent amino acids: CEIKMNPQSTWY Common amino acids: FV
pI: 7.55 Basic residues: 2
Polar residues: 1 Hydrophobic residues: 6
Hydrophobicity: 80 Boman Index: -659
Half-Life: 4.4 hour Half-Life Yeast: >20 hour
Half-Life E.Coli: >10 hour Aliphatic Index 107
Instability Index: 1128 Extinction Coefficient cystines: 0
Absorbance 280nm: 0

Literature

  • PubMed ID:  11897379
  • Title:  Evidence for the Association of FMRFamide-related Peptides With the Spermatheca of Locusta Migratoria